Joaquin Phoenix
Larry "Doc" Sportello
Josh Brolin
Lt. Det. Christian F. "Bigfoot" Bjornsen
Owen Wilson
Coy Harlingen
Katherine Waterston
Shasta Fay Hepworth
Reese Witherspoon
Deputy D.A. Penny Kimball
Benicio del Toro
Sauncho Smilax
Jena Malone
Hope Harlingen
Joanna Newsom
Sortilège
Jordan Christian Hearn
Denis
Hong Chau
Jade
Jeannie Berlin
Aunt Reet
Maya Rudolph
Petunia Leeway
Michael Kenneth Williams
Tariq Khalil
Martin Short
Dr. Rudy Blatnoyd, D.D.S.
Sasha Pieterse
Japonica Fenway
Martin Donovan
Crocker Fenway
Eric Roberts
Michael Z. Wolfmann
Serena Scott Thomas
Sloane Wolfmann
Christopher Allen Nelson
Glenn Charlock
Sam Jaeger
Agent Flatweed
Timothy Simons
Agent Borderline
Jillian Bell
Chlorinda
Taylor Bonin
Ensenada Slim
Martin Dew
Dr. Buddy Tubeside
Shannon Collis
Bambi
Catherine Haena Kim
News Reporter
Vivienne Khaledi
Amethyst Harlingen
Yvette Yates Redick
Luz
Andrew Simpson
Riggs Warbling
Joe Dioletto
Cop with Bigfoot
Jack Kelly
Burke Stodger (archive footage)
The Growlers
The Boards
Belladonna
Clancy Charlock
Alina Gatti
Howdy Doper's Phone Voice (voice)
Elaine Tan
Xandra
Wilson Bethel
LAPD Officer #1
Anders Holm
LAPD Officer #2
Emmet Unverzagt
Bigfoot's Kid
Erica Sullivan
Dr. Lily Hammer
Eva Fisher
Dr. Threeply's Assistant #1
Jackie Michele Johnson
Dr. Threeply's Assistant #2
Katie Schwartz
Kimberly
Charley Morgan
Dr. Igor
Keith Jardine
Puck Beaverton
Delaina Mitchell
Mrs. Chastity Bjornsen
Michael Cotter
Rhus Frothingham
Peter McRobbie
Adrian Prussia
Shannon C. Sullivan
Adrian Prussia's Secretary
Samantha Lemole
Golden Fang Mother
Madison Leisle
Golden Fang Daughter
Liam Van Joosten
Golden Fang Son
Matt Doyle
Golden Fang Father
Christian Williams
Smedley
Jefferson Mays
Dr. Threeply
David Prak
Buddhist Monk
Amy Ferguson
Bodhi
Emma Dumont
Zinnia
Scott Aschenbrenner
Jesus Guard (uncredited)
Christina Bobrowsky
Patient (uncredited)
Peter Bonilla
Police Officer (uncredited)
Gregoer Boru
Recording Tech (uncredited)
Marianne Bourg
Beach Girl (uncredited)
Toyia Brown
Harmony (uncredited)
Stu Brumbaugh
Groupie (uncredited)
Seth Cash
Detective (uncredited)
Laura Lyon Rossi
Groupie (uncredited)
Ashleigh Biller
Patient (uncredited)
Elizabeth Colunga
Patient (uncredited)
Emma Cooper
Groupie (uncredited)
Nick de Graffenreid
Patient (uncredited)
Adam Dorsey
Jesus Guard (uncredited)
Ken Edling
Judge (uncredited)
Jenna Emery
Groupie (uncredited)
Al Function
Biker (uncredited)
Brandy Futch
Flight Attendant (uncredited)
Lauren Goncher
Dental Assistant (uncredited)
Ellen Ho
Chinese Waitress (uncredited)
Jessica Huss
Speed Freak (uncredited)
Robert Peoples
Patient (uncredited)
Dallas James
Auto Mechanic (uncredited)
Christopher Karl Johnson
Mr. Robinson (uncredited)
Timothy Lally
Commando (uncredited)
Adeana Lane
Beach Girl (uncredited)
Kira Legg
Groupie (uncredited)
Tracy Ann Lisa
District Attorney (uncredited)
Blue LoLan
Patient (uncredited)
Jacob Lyman
Mormon FBI Agent (uncredited)
Amanda Maddox
Flight Attendant (uncredited)
Emilee Madrak
Groupie (uncredited)
Kirstin Masters
Dental Assistant (uncredited)
Zach McMahon
Police Officer (uncredited)
Chelsea O'Toole
Patient (uncredited)
Shaun Parker
Commando (uncredited)
Rodney J. Richards
Adrian Prussia's Friend (uncredited)
Philip Roosevelt
Hippie in Commune (uncredited)
Osamu Saito
Japanese Waiter (uncredited)
Joel Shock
Police Officer (uncredited)
Matthew Skomo
Detective (uncredited)
Chantal Thuy
Groupie (uncredited)
Diana Elizabeth Torres
Lourdes (uncredited)