Seth MacFarlane
Peter Griffin as Han Solo / Brian Griffin as Chewbacca / Stewie Griffin as Darth Vader / Glenn Quagmire as C-3PO / Tom Tucker as Imperial Newscaster / Carter Pewterschmidt as Uncle Owen / Safeguard #1 / Italian #2 / White Guard #2 (voice)
Alex Borstein
Lois Griffin as Princess Leia / Barbara Pewterschmidt as Aunt Beru (voice)
Seth Green
Chris Griffin as Luke Skywalker (voice)
Mila Kunis
Meg Griffin (voice)
Mike Henry
Cleveland Brown as R2-D2 / John Herbert as Obi-Wan Kenobi / Bruce the Performance Artist as Greedo / Fouad as Imperial Officer (voice)
Lori Alan
Diane Simmons as Imperial Newscaster (voice)
Rush Limbaugh
Himself / Red 6 (voice)
Tom Baker
The Doctor (archive footage)
Mark Hentemann
Opie as Tusken Raider (voice)
Phil LaMarr
Ollie Williams as Imperial Meteorologist / Redd Fox (voice)
John Viener
TV Announcer / Black Guard / Spaceguard #1 / White Guard #1 / Vader Guard #2 / Sean Connery (voice)
Leslie Nielsen
Dr. Rumack (archive voice)
Patrick Warburton
Joe Swanson as Biggs Darklighter (voice)
John G. Brennan
Mort Goldman as Jawa (as Johnny Brennan)
Steve Callaghan
Rebel Soldier (voice)
Chevy Chase
Clark Griswold (voice)
Beverly D'Angelo
Ellen Griswold (voice)
Mick Hucknall
Himself (voice)
Helen Reddy
Herself (voice)
Danny Smith
Vader Assistant 2 / Italian 1 / Vade Guard 1 / Darth Harrington (voice)
Alec Sulkin
Various Characters (voice)
Don Thai Theerathada
Thai Pilot (voice) (as Don Tai)
Adam West
Mayor Adam West as Grand Moff Tarkin (voice)
Judd Nelson
John Bender (uncredited) (voice)