Julia Roberts
Mary Reilly
John Malkovich
Dr. Henry Jekyll / Edward Hyde
George Cole
Mr. Poole
Michael Gambon
Mary’s Father
Glenn Close
Mrs. Farraday
Kathy Staff
Mrs. Kent
Michael Sheen
Bradshaw
Bronagh Gallagher
Annie
Linda Bassett
Mary's Mother
Ciarán Hinds
Sir Danvers Carew
Henry Goodman
Haffinger
Wendy Nottingham
Screaming Girl's Mother
Moya Brady
Young Woman
Emma Griffiths Malin
Young Whore
Sasha Hanau
Young Mary
Isabella Marshall
Screaming Girl
Richard Leaf
Screaming Girl's Father
Stephen Boxer
Inspector
Tim Barlow
Vicar
Harry Fielder
Man with Beard (uncredited)